MIF Regulates M1 Macrophage Polarization via CD74/CXCR2/JNK Pathway and Mediates Aortic Dissection in Mice
Lu Wang, Huishan Wang, Liming Yu, Hui Jiang, Xia Lin
This study shows MIF promotes aortic dissection by enhancing M1 macrophage polarization through the CD74/CXCR2/JNK pathway and inducing VSMC phenotypic switching.
bioRxiv · Oct 26, 2023 · PreprintMolecular Biology