Author

Lu Wang

St. Jude Children's Research HospitalORCID 0000-0001-7505-7894Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Lu Wang12 papers · St. Jude Children's Research Hospital

Biology Disciplines

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Genetic & Genomic Medicine· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:Bayesian inference· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:variant calling· 1 Research Focus:variant effect prediction· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

David A. WheeleriD· 1 shared Hui JiangiD· 1 shared Huishan WangiD· 1 shared Jamie L. MaciaszekiD· 1 shared Jeffery M. KlcoiD· 1 shared Li TangiD· 1 shared Liming YuiD· 1 shared Mohammad K. EldomeryiD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperGenetic & Genomic Medicine

David A. WheelerORCID

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2 papers

Recent·Most cited

Genetic & Genomic MedicineGenetics in MedicinePeer-reviewedSep 19, 2024

Evaluation of Bayesian Point-Based System on the Variant Classification of Hereditary Cancer Predisposition Genes

Mohammad K. Eldomery, Jamie L. Maciaszek, Taylor Cain…·Patrick R. Blackburn

The paper evaluates a Bayesian point-based system for variant classification in hereditary cancer genes, finding it reduces variants of uncertain significance compared to ACMG/AMP 2015 guidelines.

6 citations

humanwhole-exome sequencing

𝕏 PostBluesky

Molecular BiologybioRxivPreprintOct 26, 2023

MIF Regulates M1 Macrophage Polarization via CD74/CXCR2/JNK Pathway and Mediates Aortic Dissection in Mice

Lu Wang, Huishan Wang, Liming Yu…·Xia Lin

This study shows MIF promotes aortic dissection by enhancing M1 macrophage polarization through the CD74/CXCR2/JNK pathway and inducing VSMC phenotypic switching.

2 citations

mouseexperimental assay

𝕏 PostBluesky

Lu Wang · henhao