ImmunologybioRxivPreprint
Multi-Omics Reveals Activated Fibroblasts with Dual Functional Roles in Repair and Negative Barrier in the CD8+ T Cell Cytotoxic Niche for Lung Cancer Neoadjuvant Therapy
Ruihan Zhou, Chaoxin Xiao, Ping Zhou…·Chengjian Zhao
The paper introduces NICHE, a multi-omics framework to analyze immune niches in lung cancer, revealing fibroblasts with dual roles in tissue repair and immunosuppression.