Author

Chengjian Zhao

Sichuan UniversityORCID 0000-0003-0624-5263Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell-cell communication· 2 Approach:deep learning· 2 Assay:imaging· 2 Research Focus:spatial domain detection· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

Banglei Yin· 3 shared Fujun Cao· 3 shared Ruihan ZhouiD· 3 shared Tongtong XuiD· 3 shared Chaoxin XiaoiD· 2 shared Lili Jiang· 2 shared Ouying Yan· 2 shared Xiaoying LiiD· 2 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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3 shared papersCell Biology

Banglei Yin

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3 papers

Recent·Most cited

Cell BiologyeLifePeer-reviewedApr 22, 2026

A Novel 3D Visualization Method in Mice Identifies the Periportal Lamellar Complex (PLC) as a Key Regulator of Hepatic Ductal and Neuronal Branching Morphogenesis

Tongtong Xu, Fujun Cao, Ruihan Zhou…·Chengjian Zhao

The paper develops a 3D imaging method to identify the Periportal Lamellar Complex (PLC) as a structural regulator of liver ductal and neuronal branching.

DOI 10.7554/elife.108669.5

mouseimaging

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ImmunologybioRxivPreprintJan 15, 2026

Multi-Omics Reveals Activated Fibroblasts with Dual Functional Roles in Repair and Negative Barrier in the CD8+ T Cell Cytotoxic Niche for Lung Cancer Neoadjuvant Therapy

Ruihan Zhou, Chaoxin Xiao, Ping Zhou…·Chengjian Zhao

The paper introduces NICHE, a multi-omics framework to analyze immune niches in lung cancer, revealing fibroblasts with dual roles in tissue repair and immunosuppression.

DOI 10.64898/2026.01.14.699401

humanscRNA-seq

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Cancer BiologybioRxivPreprintAug 23, 2024

Pipeline for Assessing Tumor Immune Status Using Superplex Immunostaining and Spatial Immune Interaction Analysis

Chaoxin Xiao, Ruihan Zhou, Qin Chen…·Chengjian Zhao

This paper introduces a high-throughput superplex staining platform and a computer vision pipeline to analyze spatial immune interactions in tumor microenvironments.

2 citations

imagingdeep learning

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