Author

Morrie Lam

Harvard UniversityORCID 0000-0001-6580-2459Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Jason E. GestwickiiD· 1 shared M. Catarina SilvaiD· 1 shared Stephen J. HaggartyiD· 1 shared Surya A. ReisiD· 1 shared Szu-Yu KuoiD· 1 shared

Activity by Year

2023-2023 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperNeuroscience

Jason E. GestwickiORCID

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1 paper

Recent·Most cited

NeurosciencebioRxivPreprintDec 11, 2023

Cholesterol Dysregulation Drives Seed-Dependent Tau Aggregation in Patient Stem Cell-Derived Models of Tauopathy

Morrie Lam, Szu-Yu Kuo, Surya A. Reis…·Stephen J. Haggarty

This study shows that cholesterol dysregulation promotes tau aggregation in patient-derived neurons and demonstrates that tau degraders can block this effect.

2 citations

humanexperimental assay

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