Cell BiologybioRxivPreprint
Endothelial KRAS G12V signaling drives aberrant morphogenesis and establishes an AVM transcriptional identity in primary human endothelial cells
Samantha King, Qingfen Li, Ramon Bossardi Ramos, Kevin M. Pumiglia
This study shows that KRASG12V in human endothelial cells causes abnormal vessel formation and an AVM-like gene expression pattern in a 3D culture model.
DOI 10.64898/2026.06.26.734855