Ramon Bossardi Ramos

This study shows that loss of DMT1 disrupts iron homeostasis, leading to ER stress and ECM destabilization, which enhances cancer cell invasion in 3D models.

This study shows that KRASG12V in human endothelial cells causes abnormal vessel formation and an AVM-like gene expression pattern in a 3D culture model.

This study shows that lipid lowering in middle-aged mice fails to reduce atherosclerosis progression and neutrophilic inflammation, unlike in young mice.

The paper uses TRAP seq in 3D angiogenesis assays to identify endothelial-specific gene expression changes during early and late stages of morphogenesis.

This study identifies PKCε as a novel atheroprotective gene by showing its role in restricting lipid uptake in myeloid cells and reducing plaque vulnerability.

This study shows that endothelial cells retain inflammatory memory through chromatin remodeling, with JunB playing a key role in epigenetic priming after sepsis.

This study shows that deleting endomucin in endothelial cells causes structural and functional issues in kidney glomeruli, including podocyte damage and albuminuria.