Tumors Located in the Brain Impair the Frequency and Phenotype of Dendritic Cells in Blood and Tumor
Bryan Gardam, Tessa Gargett, Eunwoo Nam, Sidra Khan, Rebecca J. Ormsby, Santosh Isaac Poonnoose, Julie M Bracken, Anupama Pasam, Sakthi Lenin, Briony L. Gliddon, Melinda Nay Tea, Chloé Shard, Stuart Maxwell Pitson, Guillermo Alberto Gomez, Katherine A. Pillman, , Lisa M. Ebert
This paper identifies systemic reductions in dendritic cell (DC) numbers and activation markers in brain tumor patients, with brain tumors directly contributing to DC defects, and highlights corticosteroid use as a confounding factor.
iScience · Feb 26, 2026Peer-reviewedImmunology