Katherine A. Pillman

Tumors Located in the Brain Impair the Frequency and Phenotype of Dendritic Cells in Blood and Tumor

This paper identifies systemic reductions in dendritic cell (DC) numbers and activation markers in brain tumor patients, with brain tumors directly contributing to DC defects, and highlights corticosteroid use as a confounding factor.

Chasing non-existent microRNAs in cancer

The paper investigates whether reported miRNAs in cancer are functionally active, finding many are not incorporated into RISC and lack endogenous silencing capability.

More than half of annotated human miRNAs are never expressed at levels sufficient for biological function

The paper shows that over half of annotated human miRNAs are not expressed at biologically significant levels, challenging the validity of many miRNA function studies.

The landscape of alternative polyadenylation during EMT and its regulation by the RNA-binding protein Quaking

The paper maps alternative polyadenylation changes during EMT in human mammary epithelial cells and identifies QKI's role in regulating APA and gene expression.

Haemolysis detection in microRNA-seq from clinical plasma samples

This paper identifies a 20-miRNA signature to detect haemolysis in microRNA-seq data from clinical plasma samples.

DraculR: A web based application for in silico haemolysis detection in high throughput small RNA sequencing data

DraculR detects haemolysis contamination in small RNA sequencing data by calculating a haemolysis metric from microRNA expression data.

Post-Transcriptional Control Of EMT Is Coordinated Through Combinatorial Targeting By Multiple microRNAs

The paper shows that multiple microRNAs work together to control EMT by reducing noise and enhancing gene expression changes, more accurately reflecting endogenous regulation.