Cancer BiologyJournal of Clinical InvestigationPeer-reviewed
Replication stress marker phospho-RPA2 predicts response to platinum and PARP inhibitors in homologous recombination-proficient ovarian cancer
Angela M. Schab, Amanda J. Compadre, Rikki Drexler…·Mary Margaret Mullen
This study identifies phospho-RPA2 as a biomarker predicting response to platinum and PARP inhibitors in HR-proficient ovarian cancer, showing higher pathologic complete response and longer survival in pRPA2-High tumors.