Vivian Yeong

This study shows how charge-patterned disordered peptides influence phase separation in bacterial cells by altering condensate size, number, and location.

The paper designs short cationic peptide tags to facilitate protein phase separation in E. coli, showing they enable sequestration and maintain catalytic activity of appended enzymes.

This study engineers liquid-like biomolecular condensates in E. coli by supercharging proteins, demonstrating dynamic phase separation and enrichment of specific components.