Author

Alisha M. Birk

Gladstone InstitutesORCID 0000-0001-6631-481XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

Aradhana SachdeviD· 1 shared Bruce R. ConkliniD· 1 shared Claire Dudley ClellandiD· 1 shared HL Watry· 1 shared Janet S. Ziegle· 1 shared Kamaljot GilliD· 1 shared Kathleen C. KeoughiD· 1 shared Maria SckaffiD· 1 shared

Activity by Year

2022-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Aradhana SachdevORCID

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1 paper

Recent·Most cited

NeurosciencebioRxivPreprintMay 21, 2022

Two therapeutic CRISPR/Cas9 gene editing approaches revert FTD/ALS cellular pathology caused by a C9orf72 repeat expansion mutation in patient derived cells

Maria Sckaff, Kamaljot Gill, Aradhana Sachdev…·Claire Dudley Clelland

This study evaluates three CRISPR/Cas9 approaches to correct C9orf72 repeat expansion in patient-derived neurons, finding that repeat and mutant allele excision fully eliminate dipeptide repeats.

4 citations

humanCRISPR screen

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