Oleg S. Nikonov

This study investigates how mutant forms of glycyl-tRNA synthetase associated with Charcot-Marie-Tooth disease interact with IRES type I, finding that catalytic activity and dimerization are not required for this interaction.

The paper identifies enhanced C/EBP binding to C>T mismatches as a mechanism for selective accumulation of [C>T]G mutations in transcription factor binding sites.