Lauris Kaplinski

DIPLER identifies structurally complex loci using k-mer analysis and de novo assembly from low-coverage sequencing data.

This paper develops a k-mer-based method to design PCR primers for rapid, low-cost sequence typing of L. monocytogenes with 100% sensitivity and specificity.

KATK is a tool for variant calling from raw sequencing reads, achieving low false negative and discovery rates while avoiding bias against rare variants.

The paper analyzes transcriptomic and genomic data from Conus consors to identify protein sequences and conopeptides.

The paper validates a whole-genome sequencing-based NIPT method and software for detecting fetal aneuploidies in Estonia, showing high accuracy for common trisomies but some false positives and detection issues with low fetal fraction.

FastGT calls common SNVs from raw sequencing reads using k-mer frequency analysis, achieving high concordance with reference genotypes.

StrainSeeker identifies bacterial strains from unassembled sequencing reads using guide trees, successfully detecting Escherichia coli strains in mixed samples within 5 minutes.