eRNAformer enables genome-wide de novo mapping of enhancer-derived RNA loci
eRNAformer maps enhancer-derived RNA loci genome-wide using deep learning, identifying new eRNA loci linked to disease risk and cancer therapy.
Author
Chinese Academy of SciencesORCID 0000-0001-6691-1139Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
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eRNAformer maps enhancer-derived RNA loci genome-wide using deep learning, identifying new eRNA loci linked to disease risk and cancer therapy.
Hua Yu, Lu Lu, Ming Chen…·Jin Zhang
KDDANet identifies hidden genes mediating known drug-disease associations by analyzing genome-wide functional gene interaction networks, revealing both known and novel candidates in diseases like Alzheimer's and obesity.
Lin Yang, Yuqing Zhu, Hua Yu…·Wei Li
This paper introduces scMAGeCK, a computational framework for analyzing single-cell CRISPR screens to identify genes and non-coding elements associated with multiple phenotypes.
Hua Yu, Bingke Jiao, Chengzhi Liang
The paper constructs and analyzes RNA-seq-based gene co-expression networks in four plant species, identifying conserved and species-specific modules linked to biological functions and agronomic traits.
Hua Yu, Bingke Jiao, Chengzhi Liang
The paper builds a high-quality rice RNA-seq-based gene co-expression network using an ensemble method and demonstrates its utility for predicting gene function and regulation.