Thomas Michael O’Shea

The paper identifies placental gene-trait associations across the life course using multi-omics data, finding genetic effects on early-life traits but not later ones.

The paper uses multi-omic kernel aggregation to predict intellectual and social impairment in extremely preterm children, finding strong predictive power for IQ and SRS scores.

CUE imputes DNA methylation from HM450 to HM850 platforms, achieving lower RMSE and higher accuracy than existing methods across two cohorts.