Hudson Pires de Oliveira Santos Junior

Genetic control of fetal placental genomics contributes to development of health and disease

The paper identifies placental gene-trait associations across the life course using multi-omics data, finding genetic effects on early-life traits but not later ones.

Evidence for the Placenta-Brain Axis: Multi-Omic Kernel Aggregation Predicts Intellectual and Social Impairment in Children Born Extremely Preterm

The paper uses multi-omic kernel aggregation to predict intellectual and social impairment in extremely preterm children, finding strong predictive power for IQ and SRS scores.

CUE: CpG impUtation Ensemble for DNA Methylation Levels Across the Human Methylation450 (HM450) and EPIC (HM850) BeadChip Platforms

CUE imputes DNA methylation from HM450 to HM850 platforms, achieving lower RMSE and higher accuracy than existing methods across two cohorts.

Discrimination Exposure and DNA Methylation of Stress-Related Genes in Latina Mothers

This study examines the relationship between discrimination and DNA methylation of stress-related genes in Latina mothers, finding negative associations with methylation at specific CpG sites in NR3C1, BDNF, and FKBP5.