Author

Natasja G. de Groot

Biomedical Primate Research CentreORCID 0000-0001-6699-9345Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Genetics· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:variant calling· 3 Research Focus:database / resource· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:whole-genome sequencing· 2 Assay:long-read sequencing· 1 Organism:rat· 1

Frequent Co-Authors

Jesse BruijnesteijniD· 3 shared Ronald E. BontropiD· 3 shared Marit K. H. van der Wiel· 2 shared Ngoc Giang LeiD· 2 shared Erica M. PasiniiD· 1 shared Jesse Mittertreiner· 1 shared Nanine de Groot· 1 shared Sayed J Mohammadi· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 28 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersGenetics

Jesse BruijnesteijnORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

GeneticsBioinformaticsPeer-reviewedMar 3, 2026

VDJ-Insights: simplifying the annotation of genomic IG and TCR regions

Susan Ott, Ngoc Giang Le, Sayed J Mohammadi…·Jesse Bruijnesteijn

VDJ-Insights annotates IG and TCR loci with high accuracy, identifying novel alleles in human haplotypes.

1 citation

humanwhole-genome sequencing

𝕏 PostBluesky

GeneticsGenome ResearchPeer-reviewedNov 1, 2024

Unravelling the architecture of Major Histocompatibility Complex class II haplotypes in rhesus macaques

Nanine de Groot, Marit K. H. van der Wiel, Ngoc Giang Le…·Ronald E. Bontrop

This study characterizes the MHC class II haplotypes in rhesus macaques using long-read sequencing, revealing dynamic rearrangements and pseudogene roles.

7 citations

ratwhole-genome sequencing

𝕏 PostBluesky

Molecular BiologybioRxivPreprintMar 11, 2021

Rapid characterization of complex genomic regions using Cas9 enrichment and Nanopore sequencing

Jesse Bruijnesteijn, Marit K. H. van der Wiel, Natasja G. de Groot, Ronald E. Bontrop

The paper develops a method to rapidly characterize complex genomic regions using Cas9 enrichment and Nanopore sequencing, achieving accurate haplotype resolution in the KIR gene cluster.

1 citation

humanlong-read sequencing

𝕏 PostBluesky