Author

David S. Roos

University of PennsylvaniaORCID 0000-0001-6725-4089Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Andrea KennardiD· 1 shared Andrew R. JonesiD· 1 shared Asis KhaniD· 1 shared Daniel John RigdeniD· 1 shared Helen DavisoniD· 1 shared James Er· 1 shared Katherine GreenwaldiD· 1 shared MA Miller· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperMolecular Biology

Andrea KennardORCID

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2 papers

Recent·Most cited

BioinformaticsNucleic Acids ResearchPeer-reviewedApr 10, 2026

The promise of AlphaFold for gene structure annotation

Helen Davison, Ulrike Böhme, Shahram Mesdaghi…·Daniel John Rigden

This study uses AlphaFold 3 scores to assess gene model quality in three species, finding they strongly favor curated models and suggest combining scores from multiple tools improves accuracy.

2 citations

protein structuredeep learning

𝕏 PostBluesky

Molecular BiologybioRxivPreprintMar 31, 2021

Virulence shift in Type X Toxoplasma gondii: natural cross QTL identifies ROP33 as rodent Vir locus

Andrea Kennard, MA Miller, Asis Khan…·Michael E. Grigg

The paper identifies ROP33 as a murine virulence gene in Type X Toxoplasma gondii strains isolated from southern sea otters, showing differential pathogenicity across hosts.

4 citations

mousehuman

𝕏 PostBluesky