Author

Yuzhi Xu

New York UniversityORCID 0000-0001-6733-3721Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:deep learning· 1 Research Focus:protein design· 1 Assay:protein sequence· 1 Approach:transformer / foundation model· 1

Frequent Co-Authors

Guangyong CheniD· 1 shared Jiabin Yin· 1 shared John Z. H. ZhangiD· 1 shared Junde Xu· 1 shared Juping Huang· 1 shared Zhenjia GaniD· 1 shared Zhihao Wu· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperBiochemistry

Guangyong ChenORCID

Mutual co-authors in cluster

Author profile →

1 paper

Recent·Most cited

BiochemistryJournal of the American Chemical SocietyPeer-reviewedSep 4, 2026

CatESO: Differentiable Enzyme Sequence Optimization Guided by Substrate-Aware kcat Prediction

Zhenjia Gan, Yuzhi Xu, Junde Xu…·John Z. H. Zhang

CatESO optimizes enzyme sequences to improve catalytic turnover by integrating kcat prediction with differentiable design, achieving higher predicted activity and structural confidence than existing methods.

DOI 10.1021/jacs.6c14365

protein sequencedeep learning

𝕏 PostBluesky