Aurélien Thomas

The paper uses metabolomics to identify endocannabinoid system changes in adipose tissue during obesity-induced inflammation in mice.

This study identifies phenylacetate (PAA), a gut microbiota metabolite, as a driver of vascular niche senescence and atherosclerosis in mice through IL-6-Notch1 signaling.

This study assesses the neurotoxicity of propylene glycol butyl ether (PGBE) using a multiomic approach in human BrainSpheres, revealing effects on cell cycle, oxidative stress, and nervous system processes.

This study uses activity-based proteome profiling to analyze serum serine hydrolases in infants with abusive head trauma, finding reduced enzyme activity compared to sudden infant death syndrome.

This paper develops a polygenic risk score (metaPRS) to predict sudden cardiac arrest in patients with coronary artery disease using genetic and clinical data from two cohorts.

This study shows that acute physical exercise improves motor sequence memory, with high intensity exercise having a significant effect, and this is linked to increased anandamide levels and brain activity.

The paper introduces dbnorm, an R package to visualize and correct signal drift in metabolomics data across batches, improving the detection of true biological variation.

This study shows that moderate-intensity acute exercise improves memory consolidation in humans through increased BDNF and endocannabinoid (AEA) levels, enhancing hippocampal activity and long-term memory performance.