Enabling Megascale Microbiome Analysis with DartUniFrac
Jianshu Zhao, Daniel T. McDonald, I. Sfiligoi…·Rob D. Knight
DartUniFrac is a fast, scalable algorithm for microbiome analysis that matches the statistical performance of exact UniFrac methods.
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University of Colorado BoulderORCID 0000-0001-6843-6845Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
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Jianshu Zhao, Daniel T. McDonald, I. Sfiligoi…·Rob D. Knight
DartUniFrac is a fast, scalable algorithm for microbiome analysis that matches the statistical performance of exact UniFrac methods.
Sean S. Svihla, Manuel E. Lladser
The paper sparsifies phylogenetic covariance matrices using Haar-like wavelets and validates the statistical significance of splits in a microbial mat dataset.
Michael Hoffert, Evan D. Gorman, Manuel E. Lladser, Noah Fierer
The paper constructs a periodic table of bacterial taxa to organize and visualize bacterial diversity based on genomic trait predictions.
Antony Pearson, Manuel E. Lladser
The paper introduces latent weight to quantify contamination in symbolic datasets and applies it to DNA methylation data, finding overrepresentation of specific methylation patterns when contamination is considered.