Author

I. Sfiligoi

San Diego Supercomputer CenterORCID 0000-0002-9308-5327Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:human· 1 Assay:metagenomics· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Antonio Gonzalez· 2 shared Rob D. KnightiD· 2 shared Yuhan WengiD· 2 shared Caitlin GuccioneiD· 1 shared Catherine LozuponeiD· 1 shared Daniel McDonald· 1 shared Daniel T. McDonaldiD· 1 shared Jianshu ZhaoiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBioinformatics

Antonio Gonzalez

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Author profile →

2 papers

Recent·Most cited

Enabling Megascale Microbiome Analysis with DartUniFrac

Jianshu Zhao, Daniel T. McDonald, I. Sfiligoi, Manuel E. Lladser, Lucas Patel, Yuhan Weng, Lora A. Khatib, Samuel Degregori, Antonio Gonzalez, Catherine Lozupone, Rob D. Knight

DartUniFrac is a fast, scalable algorithm for microbiome analysis that matches the statistical performance of exact UniFrac methods.

bioRxiv · Mar 3, 2026 · PreprintBioinformatics

Community assembly modeling of microbial evolution within Barrett's esophagus and esophageal adenocarcinoma

Caitlin Guccione, I. Sfiligoi, Antonio Gonzalez, Justin P. Shaffer, Mariya Kazachkova, Yuhan Weng, Daniel McDonald, Shailja C. Shah, Samuel S. Minot, Thomas G. Paulson, William M. Grady, Ludmil B. Alexandrov, Rob D. Knight, Kit Curtius

The paper models microbial community assembly dynamics in Barrett's esophagus and esophageal adenocarcinoma, finding neutral dynamics in normal tissue and BE but not EAC, with H. pylori showing non-neutral behavior in BE non-cancer outcomes.

BMC Genomics · Feb 10, 2026Peer-reviewedCancer Biology