Author

Robert A. Amezquita

Fred Hutch Cancer CenterORCID 0000-0001-6868-7193Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Assay:scRNA-seq· 2 Research Focus:software / tool· 2 Assay:ATAC-seq· 1 Research Focus:benchmarking· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Étienne BechtiD· 2 shared Raphaël GottardoiD· 2 shared Aaron T. L. LuniD· 1 shared Charlotte SonesoniD· 1 shared Davide RissoiD· 1 shared Edward J. Zhao· 1 shared Fédérico MariniiD· 1 shared Hervé PagèsiD· 1 shared

Activity by Year

2018-2019 · peak 2/yr

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10 top collaborators · 38 mutual co-author links

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2 shared papersGenomics

Étienne BechtORCID

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3 papers

Recent·Most cited

GenomicsNature MethodsPeer-reviewedDec 2, 2019

Orchestrating Single-Cell Analysis with Bioconductor

Robert A. Amezquita, Aaron T. L. Lun, Étienne Becht…·Stephanie C. Hicks

This paper provides an overview of single-cell RNA sequencing analysis using Bioconductor, highlighting its tools and methods for handling high-dimensional data.

944 citationstop 2%

scRNA-seqstatistical model

𝕏 PostBluesky

BioinformaticsbioRxivPreprintMay 30, 2019

Reply to \"A discriminative learning approach to differential expression analysis for single-cell RNA-seq\"

Étienne Becht, Edward J. Zhao, Robert A. Amezquita, Raphaël Gottardo

The paper reproduces and extends findings from Ntranos et al., showing that MAST with Sidak p-value aggregation outperforms multivariate logistic regression on experimental scRNA-seq data.

DOI 10.1101/648733

scRNA-seqstatistical model

𝕏 PostBluesky

BioinformaticsbioRxivPreprintJan 17, 2018

marge: An API for Analysis of Motifs Using HOMER in R

Robert A. Amezquita

marge provides an R API to interface with HOMER for motif analysis, enabling parallel dataset queries and tidy results for downstream analysis.

7 citations

ATAC-seqChIP-seq

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