PhysiologyJournal of the American Heart AssociationPeer-reviewed
Inhibition of Na/H exchanger-1 in the right ventricle and lung dysfunction induced by experimental pulmonary arterial hypertension in rats
Giuseppina Milano, Melanie Reinero, Julien Puyal…·Maurice Beghetti
This study shows that inhibiting NHE-1 with rimeporide reduces right ventricular hypertrophy, pulmonary vascular remodelling, inflammation, and fibrosis in a rat model of pulmonary arterial hypertension.
6 citations