Author

Juan Pablo Nicola

Consejo Nacional de Investigaciones Científicas y TécnicasORCID 0000-0001-6974-5797Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Research Focus:database / resource· 1 Approach:deep learning· 1 Assay:DNA methylation· 1 Assay:protein sequence· 1 Assay:protein structure· 1 Research Focus:software / tool· 1

Frequent Co-Authors

Marcelo Adrian MartiiD· 2 shared Carlos Pablo ModenuttiiD· 1 shared F. Brunello· 1 shared Franco G. BrunelloiD· 1 shared Lorenzo Erra· 1 shared Mariano MartíniD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 9 mutual co-author links

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2 shared papersBioinformatics

Marcelo Adrian MartiORCID

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2 papers

Recent·Most cited

BioinformaticsPLoS Computational BiologyPeer-reviewedAug 4, 2025

Integrating AlphaFold2 Models and Clinical Data to Improve the Assessment of Short Linear Motifs (SLiMs) and Their Variants' Pathogenicity

Franco G. Brunello, Lorenzo Erra, Juan Pablo Nicola, Marcelo Adrian Marti

This paper improves SLiM variant pathogenicity assessment by integrating AlphaFold2-generated structures into MotSASi, enhancing prediction accuracy over existing tools.

1 citation

protein structuredeep learning

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Molecular BiologyBiochimiePeer-reviewedFeb 5, 2022

MotSASi: Functional Short Linear Motifs (SLiMs) prediction based on genomic single nucleotide variants and structural data

Mariano Martín, F. Brunello, Carlos Pablo Modenutti…·Marcelo Adrian Marti

The paper improves SLiM prediction by integrating variant data and structural analysis of SAS impacts, enhancing specificity and variant classification in clinical genomics.

5 citations

DNA methylationprotein sequence

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