Author

Jiaxiang Huang

Second Affiliated Hospital of Zhejiang UniversityORCID 0000-0001-7064-1231Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Assay:Hi-C· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Haoxi ChaiiD· 2 shared Lingyun Meng· 2 shared Chia‐Lin WeiiD· 1 shared Dariusz PlewczyńskiiD· 1 shared Dongmei TangiD· 1 shared Guangzhou Xiong· 1 shared Guanjing Pan· 1 shared Jin HaniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenomics

Haoxi ChaiORCID

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2 papers

Recent·Most cited

GenomicsbioRxivPreprintMay 5, 2026

Cohesin extrudes chromatin loop unidirectionally through two modes of mechanisms in human cells

Ping Wang, Lingyun Meng, Linghan Jiang…·Yijun Ruan

The paper investigates cohesin-mediated chromatin loop extrusion in human cells, revealing two dynamic modes of extrusion and showing that CTCF depletion increases extrusion activity.

1 citation

humanChIP-seq

𝕏 PostBluesky

GenomicsNature MethodsPeer-reviewedApr 29, 2025

Tri-omic mapping revealed concerted dynamics of 3D epigenome and transcriptome in brain cells

Haoxi Chai, Xingyu Huang, Guangzhou Xiong…·Yijun Ruan

The paper introduces a tri-omic method to study 3D epigenome and transcriptome dynamics in brain cells across mouse lifespan, revealing distinct genomic mechanisms in neurons and non-neuronal cells.

32 citationstop 1%

mousescATAC-seq

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