Author

Yijun Ruan

Zhejiang University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biology Disciplines

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Developmental Biology· 1 Genomics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Research Focus:clustering· 1 Research Focus:database / resource· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Ai‐Min BaoiD· 1 shared Chang LiuiD· 1 shared Changzheng YuaniD· 1 shared Chao CheniD· 1 shared Chao MaiD· 1 shared Chuanyu LiuiD· 1 shared Dan ZhouiD· 1 shared Dandan ZhangiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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1 shared paperNeuroscience

Ai‐Min BaoORCID

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Author profile →

3 papers

Recent·Most cited

Cohesin extrudes chromatin loop unidirectionally through two modes of mechanisms in human cells

Ping Wang, Lingyun Meng, Linghan Jiang, Yang Li, Jiaxiang Huang, Tiancheng YU, Haoxi Chai, Minji Kim, Xia Wang, Yijun Ruan

The paper investigates cohesin-mediated chromatin loop extrusion in human cells, revealing two dynamic modes of extrusion and showing that CTCF depletion increases extrusion activity.

bioRxiv · May 5, 2026 · PreprintGenomics

Single-cell transcriptomic atlas of mouse oocyte development from growth to ovulation

Sining Zhou, Zhenshe Lin, Yiming Liu, Chang Liu, Xinyu Yang, Meichi Yue, Hong Wu, Rui Liu, Huinan Xu, Xiaoxi Zhou, Qian Liu, Zhe Zhang, Liyun Xiao, Jingxuan Zou, Jiamei Liu, , Chuanyu Liu

This study creates a single-cell transcriptomic atlas of mouse oocyte development from growth to ovulation using a new platform and integrates transcriptomic and morphological data to identify temporal shifts in gene expression.

bioRxiv · Mar 13, 2026 · PreprintDevelopmental Biology

The China Brain Multi-omics Atlas Project (CBMAP)

Dan Zhou, Yuan Zhou, Zeyu Sun, Feiyang Ji, Dandan Zhang, Quan Wang, Yijun Ruan, Yongcheng Wang, Yimin Zhu, Xiaohui Sun, Mulin Jun Li, Changzheng Yuan, Kefu Liu, Lingyun Sun, Wenli Zhai, , Jing Zhang

The China Brain Multi-omics Atlas Project (CBMAP) creates a comprehensive molecular reference map of over 1,000 human brains to address underrepresentation in East Asian populations and advance research on aging and neuropsychiatric disorders.

Molecular Psychiatry · Sep 15, 2025Peer-reviewedNeuroscience