Author

A. Comeau

Dalhousie UniversityORCID 0000-0001-7066-7239Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 3

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 3 Assay:metagenomics· 3 Approach:statistical model· 3 Approach:benchmark study· 2 Organism:human· 2 Organism:bacteria (other)· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Morgan G. I. LangilleiD· 3 shared Dhwani DesaiiD· 2 shared Robyn WrightiD· 2 shared Akhilesh S. DhananiiD· 1 shared Casey M. A. JonesiD· 1 shared Gavin M. DouglasiD· 1 shared Jacob T. NearingiD· 1 shared Jocelyn MacDonald· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersBioinformatics

Morgan G. I. LangilleORCID

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3 papers

Recent·Most cited

JarrVis: Visualising Taxa-function relationships from meta-omic data

Dhwani Desai, A. Comeau, Morgan G. I. Langille

JarrVis is an R Shiny tool that visualizes taxa-function relationships from meta-omic data, demonstrating its utility with three case studies.

bioRxiv · Apr 13, 2025 · PreprintBioinformatics

From defaults to databases: parameter and database choice dramatically impact the performance of metagenomic taxonomic classification tools

Robyn Wright, A. Comeau, Morgan G. I. Langille

This study evaluates how tool, parameter, and database choices affect metagenomic taxonomic classification performance across different datasets and applications.

Microbial Genomics · Mar 3, 2023Peer-reviewedBioinformatics

Microbiome differential abundance methods produce disturbingly different results across 38 datasets

Jacob T. Nearing, Gavin M. Douglas, Molly G. Hayes, Jocelyn MacDonald, Dhwani Desai, Nicole E. McCormick, Casey M. A. Jones, Robyn Wright, Akhilesh S. Dhanani, A. Comeau, Morgan G. I. Langille

In 38 two-group 16S rRNA datasets, 14 differential abundance tools disagreed sharply; ALDEx2 and ANCOM-II were conservative and consistent, while edgeR and LEfSe inflated false positives.

Nature Communications · Jan 17, 2022Peer-reviewedBioinformatics✦ In-depth digest