Author

Akhilesh S. Dhanani

Dalhousie UniversityORCID 0000-0002-4204-0153Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 1 Approach:benchmark study· 1 Research Focus:benchmarking· 1 Research Focus:differential expression· 1 Organism:human· 1 Assay:metagenomics· 1 Approach:statistical model· 1

Frequent Co-Authors

A. ComeauiD· 1 shared Casey M. A. JonesiD· 1 shared Dhwani DesaiiD· 1 shared Gavin M. DouglasiD· 1 shared Jacob T. NearingiD· 1 shared Jocelyn MacDonald· 1 shared Molly G. HayesiD· 1 shared Morgan G. I. LangilleiD· 1 shared

Activity by Year

2022-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBioinformatics

A. ComeauORCID

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1 paper

Recent·Most cited

Microbiome differential abundance methods produce disturbingly different results across 38 datasets

Jacob T. Nearing, Gavin M. Douglas, Molly G. Hayes, Jocelyn MacDonald, Dhwani Desai, Nicole E. McCormick, Casey M. A. Jones, Robyn Wright, Akhilesh S. Dhanani, A. Comeau, Morgan G. I. Langille

In 38 two-group 16S rRNA datasets, 14 differential abundance tools disagreed sharply; ALDEx2 and ANCOM-II were conservative and consistent, while edgeR and LEfSe inflated false positives.

Nature Communications · Jan 17, 2022Peer-reviewedBioinformatics✦ In-depth digest