Author

Jianyu Ren

Chongqing Maternal and Child Health HospitalORCID 0000-0001-7084-4370Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2

Signature Assays, Organisms & Methods

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Assay:protein sequence· 2 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:transformer / foundation model· 1

Frequent Co-Authors

Hanli JiangiD· 2 shared Li LiniD· 2 shared Xin Yang· 2 shared Bin TaniD· 1 shared Dongliang Deng· 1 shared Hai TongiD· 1 shared Lingwei Mei· 1 shared Lubin LIUiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

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10 top collaborators · 33 mutual co-author links

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2 shared papersBioinformatics

Hanli JiangORCID

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2 papers

Recent·Most cited

BioinformaticsbioRxivPreprintAug 20, 2026

ETAP-CLF: an ESM3-based transformer attention framework for binary protein classification

Jianyu Ren, Hanli Jiang, Puchangxin Li…·Li Lin

ETAP-CLF uses ESM3 embeddings and transformer attention to classify proteins into binary categories, achieving high AUROC scores across different biological processes.

DOI 10.64898/2026.08.16.745129

protein sequencetransformer / foundation model

𝕏 PostBluesky

BioinformaticsAging CellPeer-reviewedDec 23, 2025

SenSeqNet: A Deep Learning Framework for Cellular Senescence Detection from Protein Sequences

Hanli Jiang, Dongliang Deng, Yu Lai Yuan…·Lubin LIU

SenSeqNet detects cellular senescence from protein sequences with 83.55% accuracy using a hybrid LSTM-CNN architecture and ESM-2 embeddings.

DOI 10.1111/acel.70344

protein sequencedeep learning

𝕏 PostBluesky