Author

Zachary Schrank

University of North Carolina at Chapel HillORCID 0000-0001-7128-239XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Approach:deep learning· 1 Organism:mouse· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Alex J. SmithiD· 1 shared Charles M. PerouiD· 1 shared Charlotte Helena RivasiD· 1 shared Diego A. PedrozaiD· 1 shared Fengshuo LiuiD· 1 shared Henry Shelton EarpiD· 1 shared Jeffrey M. RoseniD· 1 shared Jonathan Stuart SerodyiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Alex J. SmithORCID

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1 paper

Recent·Most cited

Cancer BiologyCancer Immunology ResearchPeer-reviewedAug 17, 2026

MERTK inhibition cooperates with immunomodulatory cyclophosphamide to induce CXCL9⁺ monocyte-macrophage programming and durable anti-tumor immunity in triple negative breast cancer

Alex J. Smith, Zachary Schrank, Nan Guan…·Jeffrey M. Rosen

This paper shows that combining MERTK inhibition with cyclophosphamide enhances anti-tumor immunity in basal-like TNBC by reprogramming macrophages and promoting CD4 T cell responses.

DOI 10.1158/2326-6066.cir-26-0278

mousescRNA-seq

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