Author

George William Schaaf

Wake Forest University Health SciencesORCID 0000-0001-7129-9474Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Genomics· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Organism:non-human primate· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

J. Mark ClineiD· 3 shared Ellen E. QuilleniD· 2 shared John D. OlsoniD· 2 shared Thomas C. RegisteriD· 2 shared Chang‐Lung LeeiD· 1 shared Dalane W. KitzmaniD· 1 shared Donna NiedzwieckiiD· 1 shared Drew Neish· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersGenomics

J. Mark ClineORCID

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3 papers

Recent·Most cited

Pseudo-observations of longevity improve detection of resilience-associated genes in the Radiation Late Effects Cohort of rhesus macaques.

Juliana H. Lawandos, Mitchell Paukner, George W. Schaaf, John D Olson, Muthuswamy Raveendran, R. Alan Harris, Jeffrey Rogers, J. Mark Cline, Ellen E Quillen

The paper uses pseudo-observations of longevity to identify resilience-associated genes in rhesus macaques exposed to radiation and aging challenges.

bioRxiv · Nov 9, 2026 · PreprintGenomics

Serum pro-N-cadherin: a biomarker of cardiac fibrosis and diastolic dysfunction in irradiated non-human primates

Paul Durham Ferrell, Drew Neish, Greg O. Dugan, George William Schaaf, John D. Olson, Kristianne Michelle Oristian, Kristofer T. Michalson, Donna Niedzwiecki, Dalane W. Kitzman, Thomas C. Register, J. Mark Cline, Salvatore Vincent Pizzo, Chang‐Lung Lee

This paper shows serum pro-N-cadherin levels correlate with cardiac fibrosis and diastolic dysfunction in irradiated non-human primates, suggesting it as a potential biomarker for radiation-related heart disease.

bioRxiv · Jun 8, 2026 · PreprintPhysiology

Developing And Internally Validating AI-Based Aging Resilience Biomarkers in Non-Human Primates

Robert F. Bennett, Jaime Lynn Speiser, John D. Olson, George William Schaaf, Thomas C. Register, Laura A. Cox, J. Mark Cline, Ellen E. Quillen

The paper develops and validates AI-based aging resilience biomarkers in non-human primates using longitudinal clinical data from baboons and rhesus macaques.

The Journals of Gerontology Series A · May 1, 2026Peer-reviewedBioinformatics