ImmunologybioRxivPreprint
Regulatory network architecture constrains inflammatory responses in tissue-resident alveolar macrophages
Sonia Kruszelnicki, Sreeparna Chakraborty, Xinge Wang…·Rachel A. Gottschalk
The paper investigates gene regulatory networks in alveolar macrophages, finding that tissue-resident macrophages have more restrained inflammatory responses due to a stabilizing network involving PU.1 and CEBP/β.