Pengyang Li

The paper shows that conserved motif vocabularies constrain genome access in cell type evolution across species.

The paper shows that injury triggers ultrafast Erk signal propagation in planarians, mediated by body-wall muscles, which is essential for regeneration.

The paper uses SAMap to compare single-cell atlases across species, identifying homologous cell types and revealing ancient cell families in animal evolution.

The paper introduces the self-assembling manifold algorithm to improve gene relevance quantification and dimensionality reduction in single-cell RNA sequencing data, showing it outperforms existing methods in identifying stem cell populations and across multiple datasets.