Dania Nanes Sarfati

Aiptasia larvae are phenotypically validated as a model of coral bleaching using high-throughput machine-learning image analysis

This paper validates Aiptasia larvae as a coral bleaching model and introduces SYMPHONY, an ML pipeline that efficiently identifies algal localization in larvae under heat stress.

CRISPR/Cas9-mutagenesis reveals that varying dependence on HSF1 is associated with differences in coral heat tolerance

The paper uses CRISPR/Cas9 to show that heat-tolerant corals rely less on HSF1 for survival during heat stress compared to heat-sensitive corals.

Explosive cytotoxicity of 'ruptoblasts' bridges hormonal surveillance and immune defense

The paper identifies ruptoblasts, a novel cytotoxic cell type in planarians, showing they use explosive cell death to release cytotoxic agents in response to activin, linking hormonal regulation to immune defense.

Coordinated wound responses in a regenerative animal-algal photosymbiotic metaorganism

This study shows that injury in the acoel Convolutriloba longifissura triggers coordinated responses between the host and its symbiotic algae, mediated by the runt transcription factor.

Single-cell analysis of Schistosoma mansoni reveals a conserved genetic program controlling germline stem cell fate