Author

Ryan C. Riddle

University of Maryland, BaltimoreORCID 0000-0001-7265-6939Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Ryan C. Riddle1 paper

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Organism:mouse· 3 Approach:statistical model· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Assay:ATAC-seq· 1

Frequent Co-Authors

Hans Tomas BjornssoniD· 3 shared Jill A. FahrneriD· 3 shared Kasper D. HanseniD· 3 shared Leandros BoukasiD· 3 shared Christine W. GaoiD· 2 shared Sheetal Chopra· 2 shared Wanying LiniD· 2 shared Priyanka KushwahaiD· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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3 shared papersGenetics

Hans Tomas BjornssonORCID

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3 papers

Recent·Most cited

GeneticsJCI InsightPeer-reviewedNov 28, 2023

Novel mouse model of Weaver syndrome displays overgrowth and excess osteogenesis reversible with KDM6A/6B inhibition

Christine W. Gao, Wanying Lin, Ryan C. Riddle…·Jill A. Fahrner

The paper creates a mouse model of Weaver syndrome and shows that inhibiting KDM6A/6B can reverse excessive osteogenesis caused by an EZH2 mutation.

29 citations

𝕏 PostBluesky

GeneticsbioRxivPreprintOct 15, 2023

Growth retardation in a mouse model of Kabuki syndrome 2 bears mechanistic similarities to Kabuki syndrome 1

Christine W. Gao, Wanying Lin, Ryan C. Riddle…·Jill A. Fahrner

This study compares growth retardation in mouse models of Kabuki syndrome 1 and 2, finding similar transcriptional profiles in their chondrocyte models.

1 citation

mousebulk RNA-seq

𝕏 PostBluesky

GeneticsJCI InsightPeer-reviewedSep 26, 2019

Precocious Chondrocyte Differentiation Disrupts Skeletal Growth in Kabuki Syndrome Mice

Jill A. Fahrner, Wan-Ying Lin, Ryan C. Riddle…·Hans Tomas Bjornsson

This study identifies disrupted endochondral ossification in Kabuki syndrome mice due to precocious chondrocyte differentiation, linking KMT2D dysfunction to altered Shox2 expression and growth retardation.

41 citations

mousebulk RNA-seq

𝕏 PostBluesky