BioinformaticsbioRxivPreprint
Poly-Exposure and Poly-Genomic Scores Implicate Prominent Roles of Non-Genetic and Demographic Factors in Four Common Diseases in the UK
Yixuan He, Chirag M. Lakhani, Arjun Kumar Manrai, Chirag J. Patel
The paper develops a poly-exposure score (PXS) to assess combined genetic and non-genetic risk factors for four diseases, showing PXS outperforms polygenic risk scores in some cases.
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