Systems BiologybioRxivPreprint
Quantitative comparison of single-cell RNA sequencing versus single-molecule RNA imaging for quantifying transcriptional noise
Neha Khetan, Binyamin Zuckerman, Giuliana Calia…·Leor S. Weinberger
This paper compares scRNA-seq and smFISH for quantifying transcriptional noise, finding that scRNA-seq algorithms generally underestimate noise compared to smFISH.