Author

Seth P. Zimmerman

Broad InstituteORCID 0000-0001-7407-2128Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:benchmark study· 1 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Alexander R. KovachiD· 1 shared Allen Thayakumar BasanthakumariD· 1 shared Ara JoiD· 1 shared Assil FahsiD· 1 shared Audrey TailloniD· 1 shared Brian GuedesiD· 1 shared Christian G. Cerda-SmithiD· 1 shared Christopher M. CounteriD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Alexander R. KovachORCID

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1 paper

Recent·Most cited

Cancer BiologyCancer DiscoveryPeer-reviewedJul 14, 2026

CDK8 Inhibition Releases the Muscle Differentiation Block in Fusion-driven Alveolar Rhabdomyosarcoma

Susu Zhang, Kathleen L. Engel, Assil Fahs…·Kimberly Stegmaier

This study identifies CDK8 inhibition as a therapeutic strategy for alveolar rhabdomyosarcoma by inducing myogenic differentiation and impairing tumor growth through a mechanism involving the Mediator kinase module, SAGA complex, and SIX4.

DOI 10.1158/2159-8290.cd-25-1171

humanbulk RNA-seq

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