BioinformaticsCell ResearchPeer-reviewed
Reconstruction of cell spatial organization based on ligand-receptor mediated self-assembly
Xianwen Ren, Guojie Zhong, Qiming Zhang…·Zemin Zhang
This paper introduces CSOmap, a computational method to infer spatial organization from scRNA-seq data, successfully reconstructing tumor microenvironments and simulating perturbations to study cellular interactions.