Ksenia G. Kuznetsova

The paper examines proteomic changes caused by MODY mutations in HNF1A and HNF1B using cell line models, finding suppressed energy metabolism and interferon signaling.

ProHap constructs protein sequence databases from phased genotypes to account for haplotypic diversity in proteomic searches.

This study improves variant peptide identification in proteomics by integrating retention time and fragmentation predictors into a proteogenomic pipeline, enhancing discrimination between correct and incorrect matches.

This paper develops an automated pipeline to collect, unify, and translate genetic variants associated with monogenic diabetes into protein sequences, creating a database for proteomics and structural biology analysis.

The paper investigates how common genetic haplotypes affect proteomic search results and identifies multi-variant peptides detectable by mass spectrometry.

The paper validates amino acid variants in proteogenomics by using multiple reads from overlapping peptides to improve variant reliability.

The paper identifies ADAR-mediated RNA editing sites in Drosophila proteomes across developmental stages and shows editing is phase-specific and enriched in synaptic and actomyosin functions.