Virion-associated influenza hemagglutinin clusters upon sialic acid binding visualized by cryo-electron tomography
Qiu Yu J. Huang, Hyunjae Ryan Kim, Kangkang Song, Nikolaus Grigorieff, James B. Munro, Celia A. Schiffer, Mohan Somasundaran
This study uses cryo-electron tomography to show that sialic acid binding causes influenza HA trimers to cluster and form triplets on virions.
Proceedings of the National Academy of Sciences · Apr 17, 2025Peer-reviewedBiophysics