Qiu Yu J. Huang

This study determines cryo-EM structures of orthoflaviviruses bound to LDLR family receptors, revealing distinct binding modes and receptor engagement mechanisms.

This study uses cryo-electron tomography to show that sialic acid binding causes influenza HA trimers to cluster and form triplets on virions.

The paper identifies resistance mutations in SARS-CoV-2 main protease against nirmatrelvir and ensitrelvir using yeast screens, finding cross-resistant mutations and reduced enzyme function.