Author

Han Wen Guo

University of California San DiegoORCID 0000-0001-7535-5621Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2

Signature Assays, Organisms & Methods

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Assay:protein sequence· 2 Approach:large language model· 1 Research Focus:protein structure prediction· 1 Research Focus:sequence-to-function modeling· 1 Approach:transformer / foundation model· 1

Frequent Co-Authors

Danielle Ann GrotjahniD· 2 shared Digvijay SinghiD· 2 shared Elizabeth VillaiD· 2 shared Pengtao XieiD· 2 shared Trey E. IdekeriD· 2 shared Eric P. XingiD· 1 shared Hamid Rahmani· 1 shared Hamidreza RahmaniiD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersBioinformatics

Danielle Ann GrotjahnORCID

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2 papers

Recent·Most cited

BioinformaticsbioRxivPreprintOct 6, 2024

ProteinAligner: A Multi-modal Pretraining Framework for Protein Foundation Models

Li Zhang, Han Wen Guo, Leah V. Schaffer…·Pengtao Xie

ProteinAligner improves protein function and property prediction by integrating sequence, structure, and literature text modalities in a multi-modal pretraining framework.

4 citations

protein sequencetransformer / foundation model

𝕏 PostBluesky

BioinformaticsbioRxivPreprintAug 19, 2024

Multi-Modal Large Language Model Enables Protein Function Prediction

Mingjia Huo, Han Wen Guo, Xingyi Cheng…·Pengtao Xie

ProteinChat is a multi-modal large language model that predicts protein functions from amino acid sequences, outperforming general-purpose LLMs and task-specific models.

10 citations

protein sequencelarge language model

𝕏 PostBluesky