Sylvia Adriana Newbold

The intracellular domain of the epilepsy protein PCDH19 regulates spine density in cortical neurons in vivo via Xlr genes.

This study shows that the intracellular domain of PCDH19 reduces spine density in cortical neurons by increasing Xlr gene expression, suggesting a role in synaptic homeostasis.

Cellular and behavioral characterization of Pcdh19 mutant mice: subtle molecular changes, increased exploratory behavior and an impact of social environment.

The paper characterizes Pcdh19 mutant mice, finding subtle molecular changes, increased exploratory behavior, and social environment effects on wild-type littermates.