Author

Jessica Griffiths

Cardiff UniversityORCID 0000-0003-3119-8999Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:differential expression· 2 Organism:human· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Harry J. WhitwelliD· 2 shared Johanna JacksoniD· 2 shared Paul McMahan MatthewsiD· 2 shared Seth G. N. GrantiD· 2 shared Andrew D. RandalliD· 1 shared Beverley NotmaniD· 1 shared Cristina Llinares-BenaderoiD· 1 shared Daniel Liang· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersNeuroscience

Harry J. WhitwellORCID

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4 papers

Recent·Most cited

NeurosciencebioRxivPreprintOct 8, 2026

Stage-specific proteomic signatures of synaptopathy in Alzheimers disease

Tatiana Georgiades, Jessica Griffiths, Fontaine Gibbs…·Johanna Jackson

The paper identifies stage-specific synaptic proteomic signatures in Alzheimer's disease and links them to plasma proteins associated with disease progression and cognitive decline.

DOI 10.64898/2026.10.02.755976

humanproteomics

𝕏 PostBluesky

NeurosciencebioRxivPreprintJan 23, 2025

A synaptic-astrocytic proteomic signature associated with synaptopathy in Alzheimer's Disease

Jessica Griffiths, Eléonore Schneegans, Harry J. Whitwell…·Johanna Jackson

This study identifies a synaptic-astrocytic proteomic signature associated with synapse loss in Alzheimer's Disease across different disease stages.

6 citations

humanproteomics

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NeuroscienceNeurobiology of DiseasePeer-reviewedMay 10, 2023

Alterations to parvalbumin-expressing interneuron function and associated network oscillations in the hippocampal - medial prefrontal cortex circuit during natural sleep in APPNL-G-F mice

Erica S Brady, Jessica Griffiths, Lilya Andrianova…·Michael T. Craig

This study examines network impairments in APPNL-G-F mice during sleep, finding NREM-specific changes in mPFC spindles and hippocampal SWRs linked to PV interneuron dysfunction.

22 citations

mouseexperimental assay

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NeuroscienceeNeuroPeer-reviewedJul 1, 2021

Cellular and behavioral characterization of Pcdh19 mutant mice: subtle molecular changes, increased exploratory behavior and an impact of social environment.

Natalia Galindo Riera, Sylvia Adriana Newbold, Monika Śledziowska…·Isabel Martínez‐Garay

The paper characterizes Pcdh19 mutant mice, finding subtle molecular changes, increased exploratory behavior, and social environment effects on wild-type littermates.

11 citations

mousebulk RNA-seq

𝕏 PostBluesky