Jaime Fabra-Beser

Developmental remodeling uncouples neural stem cell function from niche anatomy

This study shows neural stem cells can maintain function outside their normal anatomical niche, revealing plasticity in stem-cell environment relationships.

The intracellular domain of the epilepsy protein PCDH19 regulates spine density in cortical neurons in vivo via Xlr genes.

This study shows that the intracellular domain of PCDH19 reduces spine density in cortical neurons by increasing Xlr gene expression, suggesting a role in synaptic homeostasis.

Differential expression levels of Sox9 in early neocortical radial glial cells regulate the decision between stem cell maintenance and differentiation

The paper identifies Sox9 as a key regulator of neurogenic behavior in radial glial progenitors, showing its role in maintaining stem cell identity and generating upper-layer neurons.