Monocrotaline treatment of the rat predisposes to altered lipopolysaccharide-induced lung responses.
Dylan De Bellis, Timothy Penn, Evangeline Cowell, Michael J. Roach, Luke P. Kris, James McEvoy, Shailesh Bihari, Dani‐Louise Dixon, Jillian M. Carr
This study shows that monocrotaline-treated rats exhibit exaggerated lung responses to lipopolysaccharide, characterized by pro-inflammatory gene expression and increased thrombotic factors.
bioRxiv · Dec 23, 2025 · PreprintPhysiology