Author

Maria Mandelia

Institute of Cancer ResearchORCID 0000-0001-7571-6669Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Eugene KatsevichiD· 1 shared James Smith· 1 shared Jayaram VijayakrishnaniD· 1 shared Philip LawiD· 1 shared Richard S. HoulstoniD· 1 shared Timothy BarryiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperGenomics

Eugene KatsevichORCID

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1 paper

Recent·Most cited

GenomicsWellcome Open ResearchPeer-reviewedJul 30, 2026

Enhancer-gene regulatory interactions in colorectal cancer revealed through genome-wide CRISPRi perturbations

Philip Law, Jayaram Vijayakrishnan, James Smith…·Richard S. Houlston

The paper uses CRISPRi Perturb-seq to identify 238 enhancer-gene regulatory associations in colorectal cancer and integrates chromatin data to understand their spatial organization.

DOI 10.12688/wellcomeopenres.26913.1

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